Talk:Clofazimine

Pharmacology Mid‑importance

	This article is within the scope of WikiProject Pharmacology, a collaborative effort to improve the coverage of Pharmacology on Wikipedia. If you would like to participate, please visit the project page, where you can join the discussion and see a list of open tasks.PharmacologyWikipedia:WikiProject PharmacologyTemplate:WikiProject Pharmacologypharmacology articles
Mid	This article has been rated as Mid-importance on the project's importance scale.

Medicine C‑class Mid‑importance

	Medicine portal This article is within the scope of WikiProject Medicine, which recommends that medicine-related articles follow the Manual of Style for medicine-related articles and that biomedical information in any article use high-quality medical sources. Please visit the project page for details or ask questions at Wikipedia talk:WikiProject Medicine.MedicineWikipedia:WikiProject MedicineTemplate:WikiProject Medicinemedicine articles
C	This article has been given a rating which conflicts with the project-independent quality rating in the banner shell. Please resolve this conflict if possible.
Mid	This article has been rated as Mid-importance on the project's importance scale.

Ideal sources for Wikipedia's health content are defined in the guideline Wikipedia:Identifying reliable sources (medicine) and are typically review articles. Here are links to possibly useful sources of information about Clofazimine.

PubMed provides review articles from the past five years (limit to free review articles)
The TRIP database provides clinical publications about evidence-based medicine.
Other potential sources include: Centre for Reviews and Dissemination and CDC

Clofazimine edit

Latest comment: 17 years ago1 comment1 person in discussion

I have mentioned that Clofazimine is used in combination with rifampicin and dapsone as part of MDT for leprosy, as it is never used as monotherapy.--WHO Leprosy 15:46, 24 March 2007 (UTC)Reply

Stereochemistry edit

Latest comment: 9 years ago1 comment1 person in discussion

The structure image shows the imine with a specific stereochemistry, but I think it should be drawn undefined. Neither the FDA label^[1] nor the INN^[2]^[3] give any stereochemistry for the name 'clofazimine'.

Chemically, it looks like it will be quite a labile imine, so the isomers probably interconvert with the equilibrium towards the structure currently shown (away from the steric bulk of the chlorophenylamino group) TheMikrobe (talk) 12:18, 26 January 2015 (UTC)Reply

References

Add topic

[1] "FDA".

[2] "INN recommended" (PDF).

[3] "INN proposed" (PDF).

[1]

[2]

[3]