Talk:Calcium-sensing receptor

Wiki Education Foundation-supported course assignment

This article was the subject of a Wiki Education Foundation-supported course assignment, between 3 September 2020 and 14 December 2020. Further details are available on the course page. Student editor(s): GeoMedrek.

Above undated message substituted from Template:Dashboard.wikiedu.org assignment by PrimeBOT (talk) 16:32, 16 January 2022 (UTC)

Untitled

I have doubts about the validity of the part about signal transducing. This sentence "Decreased calcium binding on the extracellular side gives a conformation change in the receptor, which, on the intracellular side, initiates the phospholipase C pathway..." seems to be incorrect to me. The increase in extracellular calcium i.e. increased calcium binding to the receptor should actually activate the intracellular signalling pathway. Harmdu (talk) 18:11, 18 March 2011 (UTC)

How does increase intracellular calcium inhibit vesicle fusion it should activates it (M7 (talk) 18:18, 27 January 2013 (UTC))

Assessment comment

The comment(s) below were originally left at Talk:Calcium-sensing receptor/Comments, and are posted here for posterity. Following several discussions in past years, these subpages are now deprecated. The comments may be irrelevant or outdated; if so, please feel free to remove this section.

Factual error in article: Binding of extraccellular calcium to the calcium receptors on the parathyroid gland results in a decreased exocytosis of parathyroid hormone NOT an increase as the article states. Check out reference below. http://www.endocrine-abstracts.org/ea/0002/ea0002sp20.htm Endocrine Abstracts 2 SP20 Calcium Receptor Antagonists EF Nemeth

Last edited at 15:37, 8 June 2009 (UTC). Substituted at 10:42, 29 April 2016 (UTC)