Talk:Annealing (biology)

merge with Nucleic acid hybridization

- pretty close to the same thing. can it be treated well by a single article? -- Jethero^Talk 03:40, 13 June 2008 (UTC)

I rather like conciseness. 129.176.151.10 (talk) 16:45, 18 August 2008 (UTC)

I think 'annealing' is the proper term for this subject. These two articles are referring to the same process. I can't think of any exceptions. Theprawn46 (talk) 22:17, 21 August 2009 (UTC)

to me Annealing is quite a specific term for the hybirdization process in PCR which is under control and is intended to happen. in my opinion this are the differences and so i suggest not to merge them. plus this article may be extended by adding sections that is related to PCR such as "the optimal environment for PCR", which is highly unlikely to be suitable to include in the NA hybirdization. meaningless (talk) 06:44, 14 October 2009 (UTC)

I am not aware of annealing being used by most biologists to refer strictly to hybridization during PCR. However, a difference does exist, though it is a subtle one and probably does not warrant separating the terms into different entries. According to Weaver's [Molecular Biology], annealing is the general term, while hybridization is typically used to refer to the annealing of DNA molecules of different origins (for instance, genomic DNA being annealed to synthetic oligos, products of PCR-amplifying the same genomic region, or the genomic DNA from another member of the same organism). I would actually recommend combining DNA Denaturation, DNA Annealing, and Nucleic Acid Hybridization into a single, thorough entry. Nikolai Eroshenko (talk) 20:50, 18 December 2009 (UTC)