Simmons is an English patronymic surname. Notable people with the surname include:

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  • Kimora Lee Simmons (born 1975, as Kimora Lee Perkins), American fashion model and designer
  • Vanessa Simmons (born 1983), American fashion model and actress (daughter of Joseph Simmons)

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  • Edward E. Simmons (1911–2004), American electrical engineer and inventor of the bonded wire resistance strain gauge
  • George H. Simmons (1852–1937), editor-in-chief of the Journal of the American Medical Association and general secretary of the American Medical Association
  • Gustavus Simmons (born 1930), American cryptographer
  • Howard Ensign Simmons, Jr. (1929–1997) American chemist who discovered the Simmons–Smith reaction
  • Michelle Simmons (1967), Australian physicist
  • Norman Simmons (1915–2004), Nobel Prize winner and pioneer in DNA research
  • Nancy Simmons, American Zoologist specialising in the study of bats

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