(Roman Catholic) Diocese of Santo Domingo may refer to the following ecclesiastical jurisdictions in Latin America with a see called Santo Domingo (after Saint Dominic) :
- the present Roman Catholic Diocese of Santo Domingo in Ecuador
- the Antillian former Roman Catholic Archdiocese of Santo Domingo#History in the Dominican Republic, now a Metropolitan Archdiocese
This disambiguation page lists articles associated with the title Roman Catholic Diocese of Santo Domingo.
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