Robert Semple may refer to:
- Robert Sample (died 1719), or Semple, pirate who left Edward England to sail the Caribbean
- Robert Semple (Canada) (1777–1816), governor of the Red River Colony in Canada
- Robert Semple (Medal of Honor) (1887–1943), Medal of Honor recipient
- Robert B. Semple (1806–1854), California newspaperman & politician, who helped found Benicia, California
- Robert B. Semple Jr. (born 1936), 1996 Pulitzer Prize winner
- Bob Semple (1873–1955), New Zealand politician
- Robert James Semple, Irish missionary, first husband of Aimee Semple McPherson
This disambiguation page lists articles about people with the same name.
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