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Ribbon model of CCR5 (yellow), shown within the cell membrane (grey and red)

CCR5 is a human membrane protein that acts as a secondary receptor for HIV, enabling the viral and cell membranes to fuse. People with two copies of a mutated Δ32 form of CCR5 are naturally resistant to infection by most strains of HIV, and the normal form is the target of entry inhibitors such as maraviroc.

Credit: Thomas Splettstoesser (18 July 2012)