- May 10
- 1869 – The golden spike is driven at Promontory Summit, Utah, (pictured) on the First Transcontinental Railroad in North America.
- 1893 – New York Central locomotive number 999 pulls a passenger train between Batavia and Buffalo, New York, reaching 112.5 mph (181.1 km/h); this is the first time an American train breaks 100 mph (160 km/h).
- 2002 – The Potters Bar rail crash occurs at Potters Bar, north of London, England, when a northbound passenger train derails at high speed, killing seven and seriously injuring another eleven.
- 2004 – Canadian National Railway acquires Bessemer and Lake Erie Railroad and Duluth, Missabe and Iron Range Railway.
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