March 21
- 1932 – One of the deadliest tornado outbreaks in U.S. history struck the Midwestern and Southeastern United States, killing at least 330 people and injuring more than 2,000. A single F4 tornado killed an estimate 49 people in central Alabama, marking it as the state's deadliest tornado until 2011.
- 1952 – A major tornado outbreak killed more than 202 people in the Southeastern United States and injured more than 1,100. An F4 tornado devastated Judsonia, Arkansas and nearby rural areas, killing 50 people and injuring 325. Other tornadoes inflicted major death tolls in Cotton Plant, Arkansas (29 killed), Henderson, Tennessee (23), and Cooter, Missouri (17).