- 1 November
- 1860 – A boiler explosion on a locomotive at King's Cross station kills 2.
- 1864 – Thames Valley Railway opens line from Strawberry Hill Junction to Shepperton.
- 1865 – Broad Street station opens as the City of London terminus of the North London Railway.
- 1875 – Bishopsgate station closes to passengers, remaining in use as a goods station.