Plum Run may refer to:
- Plum Run (Rock Creek), a stream in Pennsylvania
- Plum Run (White Run), a stream in Pennsylvania
- Plum Run (Chartiers Run tributary), a stream in Washington County, Pennsylvania
- Plum Run (Tenmile Creek tributary), a stream in Washington County, Pennsylvania
- Plum Run, West Virginia, an unincorporated community in Tyler County
This disambiguation page lists articles about distinct geographical locations with the same name.
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