Pancreatic elastase II (EC 3.4.21.71, pancreatic elastase 2) is an enzyme.[1][2] This enzyme catalyses the following chemical reaction
| Pancreatic elastase II | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.4.21.71 | ||||||||
| CAS no. | 75603-19-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- Preferential cleavage: Leu-, Met- and Phe-. Hydrolyses elastin
This peptidase from trypsin family is formed by activation of proelastase II from mammalian pancreas by trypsin.
References edit
- ^ Fletcher TS, Shen WF, Largman C (November 1987). "Primary structure of human pancreatic elastase 2 determined by sequence analysis of the cloned mRNA". Biochemistry. 26 (23): 7256–61. doi:10.1021/bi00397a010. PMID 3427074.
- ^ Shirasu Y, Yoshida H, Matsuki S, Takemura K, Ikeda N, Shimada Y, Ozawa T, Mikayama T, Iijima H, Ishida A (December 1987). "Molecular cloning and expression in Escherichia coli of a cDNA encoding human pancreatic elastase 2". Journal of Biochemistry. 102 (6): 1555–63. doi:10.1093/oxfordjournals.jbchem.a122204. PMID 2834346.
External links edit
- Pancreatic+elastase+II at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
