Pleckstrin-2 is a protein that in humans is encoded by the PLEK2 gene .[5] [6] [7] Homo sapiens and is flanked by TMEM229B to its right and ATP6V1D to its left.[8]
References
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^ a b c GRCh38: Ensembl release 89: ENSG00000100558 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021118 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^
Lemmon, Mark A. ; Ferguson, Kathryn M.; Abrams, Charles S. (2002). "Pleckstrin homology domains and the cytoskeleton" . FEBS Letters . 513 (1): 71–76. doi :10.1016/S0014-5793(01)03243-4 PMID 11911883 .
^ Hamaguchi N, Ihara S, Ohdaira T, Nagano H, Iwamatsu A, Tachikawa H, Fukui Y (Aug 2007). "Pleckstrin-2 selectively interacts with phosphatidylinositol 3-kinase lipid products and regulates actin organization and cell spreading". Biochem Biophys Res Commun . 361 (2): 270–5. doi :10.1016/j.bbrc.2007.06.132 . PMID 17658464 . ^ "Entrez Gene: PLEK2 pleckstrin 2" .^ "AceView: PLEK2 gene" . AceView . National Library of Medicine. Retrieved 24 April 2011 .
Further reading
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Bach TL, Kerr WT, Wang Y, et al. (2007). "PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization" . Blood . 109 (3): 1147–55. doi :10.1182/blood-2006-02-001339 . PMC 1785144 PMID 17008542 . Inazu T, Kuroiwa A, Matsuda Y, Miyamoto K (2005). "Cloning, expression and chromosomal assignment of human pleckstrin 2". Mol. Biol. Rep . 32 (1): 35–40. doi :10.1007/s11033-004-4747-x . PMID 15865208 . S2CID 8131790 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Inazu T, Yamada K, Miyamoto K (1999). "Cloning and expression of pleckstrin 2, a novel member of the pleckstrin family". Biochem. Biophys. Res. Commun . 265 (1): 87–93. doi :10.1006/bbrc.1999.1461 . PMID 10548495 . Hu MH, Bauman EM, Roll RL, et al. (1999). "Pleckstrin 2, a widely expressed paralog of pleckstrin involved in actin rearrangement" . J. Biol. Chem . 274 (31): 21515–8. doi :10.1074/jbc.274.31.21515 PMID 10419454 . Hillier LD, Lennon G, Becker M, et al. (1997). "Generation and analysis of 280,000 human expressed sequence tags" . Genome Res . 6 (9): 807–28. doi :10.1101/gr.6.9.807 PMID 8889549 .
