Beta-parvin is a protein that in humans is encoded by the PARVB gene .[5] [6] [7]
Members of the parvin family, including PARVB, PARVA and PARVG , are actin-binding proteins associated with focal contacts.[supplied by OMIM][7]
References
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^ a b c GRCh38: Ensembl release 89: ENSG00000188677 – Ensembl , May 2017^ a b c GRCm38: Ensembl release 89: ENSMUSG00000022438 – Ensembl , May 2017^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .^ Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics" . Genome Res . 10 (5): 703–13. doi :10.1101/gr.10.5.703 . PMC 310876 PMID 10810093 . ^ Olski TM, Noegel AA, Korenbaum E (Feb 2001). "Parvin, a 42 kDa focal adhesion protein, related to the alpha-actinin superfamily". J Cell Sci . 114 (Pt 3): 525–38. doi :10.1242/jcs.114.3.525 . PMID 11171322 . ^ a b "Entrez Gene: PARVB parvin, beta" .
Further reading
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Dunham I, Shimizu N, Roe BA, et al. (1999). "The DNA sequence of human chromosome 22" . Nature . 402 (6761): 489–95. Bibcode :1999Natur.402..489D . doi :10.1038/990031 PMID 10591208 . Yamaji S, Suzuki A, Sugiyama Y, et al. (2001). "A novel integrin-linked kinase-binding protein, affixin, is involved in the early stage of cell-substrate interaction" . J. Cell Biol . 153 (6): 1251–64. doi :10.1083/jcb.153.6.1251 . PMC 2192033 PMID 11402068 . Korenbaum E, Olski TM, Noegel AA (2002). "Genomic organization and expression profile of the parvin family of focal adhesion proteins in mice and humans". Gene . 279 (1): 69–79. doi :10.1016/S0378-1119(01)00743-0 . PMID 11722847 . Yamaji S, Suzuki A, Kanamori H, et al. (2002). "Possible role of ILK-affixin complex in integrin-cytoskeleton linkage during platelet aggregation". Biochem. Biophys. Res. Commun . 297 (5): 1324–31. doi :10.1016/S0006-291X(02)02381-1 . PMID 12372433 . Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. Bibcode :2002PNAS...9916899M . doi :10.1073/pnas.242603899 PMC 139241 PMID 12477932 . Rosenberger G, Jantke I, Gal A, Kutsche K (2003). "Interaction of alphaPIX (ARHGEF6) with beta-parvin (PARVB) suggests an involvement of alphaPIX in integrin-mediated signaling" . Hum. Mol. Genet . 12 (2): 155–67. doi :10.1093/hmg/ddg019 PMID 12499396 . Collins JE, Goward ME, Cole CG, et al. (2003). "Reevaluating human gene annotation: a second-generation analysis of chromosome 22" . Genome Res . 13 (1): 27–36. doi :10.1101/gr.695703 . PMC 430954 PMID 12529303 . Mishima W, Suzuki A, Yamaji S, et al. (2004). "The first CH domain of affixin activates Cdc42 and Rac1 through alphaPIX, a Cdc42/Rac1-specific guanine nucleotide exchanging factor" . Genes Cells . 9 (3): 193–204. doi :10.1111/j.1356-9597.2004.00717.x PMID 15005707 . Yamaji S, Suzuki A, Kanamori H, et al. (2004). "Affixin interacts with alpha-actinin and mediates integrin signaling for reorganization of F-actin induced by initial cell-substrate interaction" . J. Cell Biol . 165 (4): 539–51. doi :10.1083/jcb.200308141 . PMC 2172344 PMID 15159419 . Zhang Y, Chen K, Tu Y, Wu C (2004). "Distinct roles of two structurally closely related focal adhesion proteins, alpha-parvins and beta-parvins, in regulation of cell morphology and survival" . J. Biol. Chem . 279 (40): 41695–705. doi :10.1074/jbc.M401563200 PMID 15284246 . Mongroo PS, Johnstone CN, Naruszewicz I, et al. (2004). "Beta-parvin inhibits integrin-linked kinase signaling and is downregulated in breast cancer" . Oncogene . 23 (55): 8959–70. doi :10.1038/sj.onc.1208112 PMID 15467740 . Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 PMID 15489334 . Matsuda C, Kameyama K, Tagawa K, et al. (2005). "Dysferlin interacts with affixin (beta-parvin) at the sarcolemma" . J. Neuropathol. Exp. Neurol . 64 (4): 334–40. doi :10.1093/jnen/64.4.334 PMID 15835269 . Ewing RM, Chu P, Elisma F, et al. (2007). "Large-scale mapping of human protein-protein interactions by mass spectrometry" . Mol. Syst. Biol . 3 (1): 89. doi :10.1038/msb4100134 . PMC 1847948 PMID 17353931 .
