The enzyme oleoyl-[acyl-carrier-protein] hydrolase (EC 3.1.2.14) catalyzes the reaction
| acyl-ACP thioesterase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 3.1.2.14 | ||||||||
| CAS no. | 68009-83-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| Gene Ontology | AmiGO / QuickGO | ||||||||
| |||||||||
- an oleoyl-[acyl-carrier-protein] + H2O an [acyl-carrier-protein] + oleate
This enzyme belongs to the family of hydrolases, specifically those acting on thioester bonds. The systematic name is oleoyl-[acyl-carrier-protein] hydrolase. Other names in common use include acyl-[acyl-carrier-protein] hydrolase, acyl-ACP-hydrolase, acyl-acyl carrier protein hydrolase, oleoyl-ACP thioesterase, and oleoyl-acyl carrier protein thioesterase. This enzyme participates in fatty acid biosynthesis.
Structural studies edit
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 2OWN and 2PFF.
References edit
- Ohlrogge JB, Shine WE, Stumpf PK (1978). "Fat metabolism in higher plants. Characterization of plant acyl-ACP and acyl-CoA hydrolases". Arch. Biochem. Biophys. 189 (2): 382–91. doi:10.1016/0003-9861(78)90225-4. PMID 30409.
- Shine WE, Mancha M, Stumpf PK (1976). "Fat metabolism in higher plants. The function of acyl thioesterases in the metabolism of acyl-coenzymes A and acyl-acyl carrier proteins". Arch. Biochem. Biophys. 172 (1): 110–6. doi:10.1016/0003-9861(76)90054-0. PMID 3134.
