OR4P4

Olfactory receptor 4P4 is a protein that in humans is encoded by the OR4P4 gene.

OR4P4
Identifiers
Aliases	OR4P4, OR4P3P, olfactory receptor family 4 subfamily P member 4
External IDs	HomoloGene: 84576; GeneCards: OR4P4; OMA:OR4P4 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11q11 Start 55,635,113 bp End 55,640,309 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in liver multicellular organism n/a More reference expression data BioGPS n/a
Gene ontology Molecular function G protein-coupled receptor activity olfactory receptor activity transmembrane signaling receptor activity signal transducer activity Cellular component integral component of membrane plasma membrane membrane Biological process sensory perception of smell detection of chemical stimulus involved in sensory perception of smell detection of chemical stimulus involved in sensory perception signal transduction response to stimulus G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 81300 n/a Ensembl ENSG00000181927 n/a UniProt Q8NGL7 n/a RefSeq (mRNA) NM_001004124 NM_001405919 n/a RefSeq (protein) NP_001004124 n/a Location (UCSC) Chr 11: 55.64 – 55.64 Mb n/a PubMed search n/a
Wikidata
View/Edit Human

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Fuchs T, Malecova B, Linhart C, Sharan R, Khen M, Herwig R, Shmulevich D, Elkon R, Steinfath M, O'Brien JK, Radelof U, Lehrach H, Lancet D, Shamir R (September 2002). "DEFOG: a practical scheme for deciphering families of genes". Genomics. 80 (3): 295–302. doi:10.1006/geno.2002.6830. PMID 12213199.

External links

• OR4P4+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.