Merrill W. Chase (September 17, 1905 – January 5, 2004) was an immunologist working at Rockefeller University in New York City who is credited with discovering cell-mediated immunology in the early 1940s. While working with Dr. Karl Landsteiner, Dr. Chase discovered that white blood cells, and not antibodies alone, were important instruments of the immune system. His findings laid the groundwork for later research that discovered the role of B cells, T cells and other types of white blood cells.[1] Recognizing that other scientists were discovering multiple functions of the immune system, he established an independent Immunology laboratory at Rockefeller.[2]

Merrill Chase
Portrait of Merrill Chase in the 1960s
BornSeptember 17, 1905
Providence, RI
DiedJanuary 05, 2004
NationalityAmerican
Alma materBrown University
Known forT cell, B cell
Scientific career
FieldsImmunologist

References

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  • Chase, M W (1989). "Early days in cellular immunology". Allergy and Asthma Proceedings. 9 (6): 683–7. doi:10.2500/108854188778965438. PMID 3066695.
  • Chase, M W (1985). "Immunology and experimental dermatology". Annu. Rev. Immunol. 3: 1–29. doi:10.1146/annurev.iy.03.040185.000245. PMID 3904768.
  • Battisto, J R (1982). "Immunological tolerance to self and non-self. Opening remarks and appreciation". Ann. N. Y. Acad. Sci. 392 (1): ix–xi. Bibcode:1982NYASA.392D...9B. doi:10.1111/j.1749-6632.1982.tb36092.x. PMID 6753688. S2CID 85233786.