Mary Bradford may refer to:

  • Mary C. C. Bradford (1856–?), first woman to be elected to a seat in the 1908 Democratic National Convention
  • Mary D. Bradford (1856–1943), first woman in Wisconsin, USA to serve as Superintendent of a major city school system
  • Mary H. Bradford, American blues singer, songwriter, composer, and lyricist
  • Mary Lythgoe Bradford (born 1930), American editor and poet significant to Mormon literature