Margaret II may refer to:
- Margaret II, Countess of Flanders (1202–1280), countess of Flanders and Hainaut, aka Margaret of Constantinople
- Margaret II, Countess of Hainault (1311–1356), Countess of Hainaut and Countess of Holland
- Margaret II, Countess Palatine of Burgundy (1350–1405), Countess of Flanders & Artois; Countess Palatine of Burgundy; Duchess of Burgundy
- Margrethe II of Denmark (born 1940), queen regnant of Denmark
This disambiguation page lists articles about people with the same name.
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