MOGAT3

MOGAT3
Identifiers
Aliases	MOGAT3, DC7, DGAT2L7, MGAT3, DGAT2L2, monoacylglycerol O-acyltransferase 3
External IDs	OMIM: 610184 HomoloGene: 80517 GeneCards: MOGAT3
Gene location (Human)
Chr.	Chromosome 7 (human)
End	101,201,038 bp
RNA expression pattern
	Top expressed in
	rectum; ; right lobe of liver; ; duodenum; ; jejunal mucosa; ; appendix; ; kidney; ; smooth muscle tissue; ; blood; ; fundus; ; islet of Langerhans;
	n/a
	More reference expression data
	n/a
Gene ontology
Molecular function	acyltransferase activity; acyltransferase activity, transferring groups other than amino-acyl groups; transferase activity; diacylglycerol O-acyltransferase activity; 2-acylglycerol O-acyltransferase activity;
Cellular component	membrane; integral component of membrane; endoplasmic reticulum; endoplasmic reticulum membrane;
Biological process	lipid metabolism; glycerol metabolic process; triglyceride biosynthetic process;
	Sources:Amigo / QuickGO
Orthologs
	346606
	n/a
	ENSG00000106384
	n/a
	Q86VF5
	n/a
	NM_001287147; NM_178176
	n/a
	NP_001274076; NP_835470
	n/a
	Wikidata
View/Edit Human

Monoacylglycerol O-acyltransferase 3 is a protein that in humans is encoded by the MOGAT3 gene.^[3]

Function edit

Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA.^[4]

References edit

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000106384 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Monoacylglycerol O-acyltransferase 3".
^ Cheng D, Nelson TC, Chen J, Walker SG, Wardwell-Swanson J, Meegalla R, Taub R, Billheimer JT, Ramaker M, Feder JN (Apr 2003). "Identification of acyl coenzyme A:monoacylglycerol acyltransferase 3, an intestinal specific enzyme implicated in dietary fat absorption". The Journal of Biological Chemistry. 278 (16): 13611–4. doi:10.1074/jbc.C300042200. PMID 12618427.

Further reading edit

Winter A, van Eckeveld M, Bininda-Emonds OR, Habermann FA, Fries R (2003). "Genomic organization of the DGAT2/MOGAT gene family in cattle (Bos taurus) and other mammals". Cytogenetic and Genome Research. 102 (1–4): 42–7. doi:10.1159/000075723. PMID 14970677. S2CID 25524277.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 7 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000106384 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-3] "Entrez Gene: Monoacylglycerol O-acyltransferase 3".

[4] Cheng D, Nelson TC, Chen J, Walker SG, Wardwell-Swanson J, Meegalla R, Taub R, Billheimer JT, Ramaker M, Feder JN (Apr 2003). "Identification of acyl coenzyme A:monoacylglycerol acyltransferase 3, an intestinal specific enzyme implicated in dietary fat absorption". The Journal of Biological Chemistry. 278 (16): 13611–4. doi:10.1074/jbc.C300042200. PMID 12618427.

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