M108 or M-108 may refer to
- M-108 highway (Michigan), a road in the United States
- M108 Howitzer, an American self-propelled 105 mm howitzer
- HMS Grimsby (M108), a minehunter in the Royal Navy
- Messier 108, a spiral galaxy in the constellation Ursa Major
This disambiguation page lists articles associated with the same title formed as a letter–number combination.
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