Louse Creek may refer to:
- Louse Creek (Alaska), a stream in Aleutians West Census Area
- Louse Creek (Missouri)
- Louse Creek (Niobrara River tributary), a stream in Holt County, Nebraska
- Louse Creek (South Dakota)
- Louse Creek (Tennessee), a stream in Lincoln County
This disambiguation page lists articles about distinct geographical locations with the same name.
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