Labdane
| Labdane | |
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(4aR,5S,6S,8aS)- 1,1,4a,6-tetramethyl-5- [(3R)-3-methylpentyl]decalin |
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| Identifiers | |
| CAS number | 561-90-0 |
| PubChem | 9548711 |
| ChemSpider | 7827634  |
| ChEBI | CHEBI:36505 |
| ChEMBL | CHEMBL1087749 |
| Jmol-3D images | Image 1 |
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| Properties | |
| Molecular formula | C20H38 |
| Molar mass | 278.516 |
 (verify) (what is:  / ?)Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) |
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| Infobox references | |
Labdane is a natural bicyclic diterpene. It forms the structural core for a wide variety of natural products collectively known as labdanes or labdane diterpenes. The labdanes were so named because the first members of the class were originally obtained from labdanum, a resin derived from rockrose plants.[1][2]
A variety of biological activities have been determined for labdane diterpenes including antibacterial, antifungal, antiprotozoal, and anti-inflammatory activities.[3]
Examples
- Forskolin
- Stemodene
- Isocupressic acid, a labdane diterpenoid, is an abortifacient component of Cupressus macrocarpa.[4]
References
- ^ Cocker, J. D.; Halsall, T. G.; Bowers, A. (1956). "The chemistry of gum labdanum. I. Some acidic constituents". Journal of the Chemical Society: 4259–62.
- ^ Cocker, J. D.; Halsall, T. G. (1956). "The chemistry of gum labdanum. II. The structure of labdanolic acid". Journal of the Chemical Society: 4262–71.
- ^ Studies in Natural Product Chemistry : Bioactive Natural Products, Part F, Atta-Ur-Rahman (Editor), ISBN 978-0-08-044001-9
- ^ Isocupressic acid, an abortifacient component of Cupressus macrocarpa. K. Parton, D. Gardner and N.B. Williamson, New Zealand Veterinary Journal, 1996, Volume 44, Issue 3, doi:10.1080/00480169.1996.35946
