|Systematic (IUPAC) name|
|Mol. mass||355.428 g/mol|
| (what is this?)
LY-307,452 is a drug used in neuroscience research, which was among the first compounds found that acts as a selective antagonist for the group II metabotropic glutamate receptors (mGluR2/3), and was useful in early studies of this receptor family, although it has largely been replaced by newer drugs such as LY-341,495.
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- Li XC, Beart PM, Monn JA, Jones NM, Widdop RE (October 1999). "Type I and II metabotropic glutamate receptor agonists and antagonists evoke cardiovascular effects after intrathecal administration in conscious rats". British Journal of Pharmacology 128 (3): 823–9. doi:10.1038/sj.bjp.0702850. PMC 1571690. PMID 10516668.
- Sung KW, Choi S, Lovinger DM (November 2001). "Activation of group I mGluRs is necessary for induction of long-term depression at striatal synapses". Journal of Neurophysiology 86 (5): 2405–12. PMID 11698530.
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