LDI may refer to:
- Lady Davis Institute for Medical Research in Montreal, Canada
- Lawrenceburg Distillers Indiana, a distillery
- Liberty Diversified Industries
- Liability-driven investment strategy
- IATA airport code for Lindi Airport
- LVDS Display Interface, a low-voltage differential signaling interface for flat-panel displays
- Laser Direct Imaging, a type of photoplotting
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