KPLO may refer to:
- KPLO-TV, a television station (channel 13 digital) licensed to Reliance, South Dakota, United States, rebroadcasting KELO-TV
- KPLO-FM, a radio station (94.5 FM) licensed to Reliance, South Dakota, United States
- Korea Pathfinder Lunar Orbiter, the first lunar exploration mission by the Korea Aerospace Research Institute.
This disambiguation page lists articles about radio and/or television stations with the same/similar call signs or branding.
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