Jenny Carmeron Taylor is a British geneticist who is Professor of Genomic Medicine at the University of Oxford. Taylor is the Director of the Oxford Biomedical Research Centre Genetics Theme. Her research considers whole genome sequencing and ways to integrate genetic research into the National Health Service.
Jenny Taylor | |
|---|---|
| Born | Jenny Carmeron Taylor |
| Alma mater | University of Oxford (BA, DPhil) |
| Scientific career | |
| Fields | Translational genomics |
| Institutions | Weatherall Institute of Molecular Medicine University of Oxford |
| Thesis | Molecular interactions of P-glycoprotein (1997) |
| Website | www |
Early life and education edit
Taylor was an undergraduate student at the St Edmund Hall, Oxford.[1][2] She remained in Oxford for her doctoral research, joining the Weatherall Institute of Molecular Medicine.[3][1]
Research and career edit
After graduating she joined a start-up company focusing on the genetics of diseases.[1] In 2002, Taylor moved to the Oxford Genetics Knowledge Park.[1] She was Director of the Oxford Biomedical Research Centre Genetics Theme, which is supported by the Department of Health and Social Care.[4] In this capacity, she oversees partnerships between researchers working in genetics and physicians in the National Health Service. In particular, she has developed novel ways to perform DNA sequencing. She hopes that these capabilities will be deployed across the health service, allowing for monitoring of the subtle changes in DNA that take place in various medical conditions.[5] She worked in collaboration with Illumina to show that in whole genome sequencing could be used to diagnose patients with genetic disorders with a greater sensitivity than conventional genetic testing.[6] These technologies – which can check 20,000 genes at the same as opposed to checking individual genes sequentially – offer hope for patients with rare diseases.[6] Accurate diagnoses can enable physicians to select the correct medication or to set up the appropriate levels of support for people with learning disabilities.[6] In 2013, she was elected a Fellow by special election at the University of Oxford.
Publications edit
Her publications[7][8] include:
- A genome-wide association study of global gene expression[9]
- Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas[10]
- Reassessment of Mendelian gene pathogenicity using 7,855 cardiomyopathy cases and 60,706 reference samples[11]
References edit
- ^ a b c d "Jenny Taylor, Fellow by Special Election in Human Genetics". seh.ox.ac.uk. St Edmund Hall, Oxford. Retrieved 7 April 2022.
- ^ "Women Inspire: An Introduction to the Exhibition" (PDF). seh.ox.ac.uk.
- ^ Taylor, Jenny Carmeron (1997). Molecular interactions of P-glycoprotein. ox.ac.uk (DPhil thesis). University of Oxford. OCLC 53668171. EThOS uk.bl.ethos.363732.
- ^ "Jenny Taylor". well.ox.ac.uk. Retrieved 7 April 2022.
- ^ "Professor Jenny Taylor". ox.ac.uk. University of Oxford. Retrieved 7 April 2022.
- ^ a b c University, Oxford. "Project brings whole genome sequencing into the clinic". medicalxpress.com. Retrieved 7 April 2022.
- ^ Jenny Taylor publications indexed by the Scopus bibliographic database. (subscription required)
- ^ Jenny Taylor publications from Europe PubMed Central
- ^ Dixon AL; Liang L; Moffatt MF; et al. (October 2007). "A genome-wide association study of global gene expression". Nature Genetics. 39 (10): 1202–7. doi:10.1038/NG2109. ISSN 1061-4036. PMID 17873877. Wikidata Q29614592.
- ^ Claire Palles; Jean-Baptiste Cazier; Kimberley M Howarth; et al. (February 2013). "Germline mutations affecting the proofreading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas". Nature Genetics. 45 (2): 136–44. doi:10.1038/NG.2503. ISSN 1061-4036. PMC 3785128. PMID 23263490. Wikidata Q24617520. (erratum)
- ^ Roddy Walsh; Kate Thomson; James Ware; et al. (17 August 2016). "Reassessment of Mendelian gene pathogenicity using 7,855 cardiomyopathy cases and 60,706 reference samples". Genetics in Medicine. 19 (2): 192–203. doi:10.1038/GIM.2016.90. ISSN 1098-3600. PMC 5116235. PMID 27532257. Wikidata Q37424109.