Sir James Sexton (1856–1938) was British trade union leader and politician.
James Sexton may also refer to:
- James A. Sexton (1844–1899), American soldier, businessman and politician
- James Sexton (attorney) (born 1972), American family law attorney
- Buck Sexton (James Buckman Sexton, born 1981), American radio and television talk show host, author and conservative political commentator
This disambiguation page lists articles about people with the same name.
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