Inosine pranobex (BAN; also known as inosine acedoben dimepranol (INN) or methisoprinol) is an antiviral drug that is a combination of inosine and dimepranol acedoben (a salt of acetamidobenzoic acid and dimethylaminoisopropanol) in a ratio of 1 to 3. Inosine pranobex has no effect on viral particles itself.[citation needed] Instead, it acts as an immunostimulant, an analog of thymus hormones.[1]

Isoprinosine
INN: Inosine acedoben dimepranol
Chemical structures of the three components of inosine pranobex (from top to bottom: inosine, acedoben and dimethylamino isopropanol)
Combination of
InosineImmunostimulant
DimethylaminoisopropanolImmunostimulant
AcedobenImmunostimulant
Clinical data
Trade namesImunovir, Delimmun, Isoprinosine,IsoJol
Other namesMethisoprinol
AHFS/Drugs.comhttps://www.drugs.com/international/isoprinosine-500mg.html
Routes of
administration
Oral
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Identifiers
PubChem CID
ChemSpider
UNII
KEGG
ECHA InfoCard100.048.313 Edit this at Wikidata

Inosine pranobex has been used in SSPE, herpes simplex virus, human papillomavirus, HIV, influenza virus, and airway virus infections, cytomegalovirus, and Epstein-Barr virus infections.[2] The effect on SSPE is unclear, it is not a cure for it.[3]

References edit

  1. ^ "Inosine Pranobex". American Cancer Society. Archived from the original on 23 August 2010. Retrieved 31 July 2013.
  2. ^ Hashimoto K, Hosoya M (January 2021). "Advances in Antiviral Therapy for Subacute Sclerosing Panencephalitis". Molecules. 26 (2): 427. doi:10.3390/molecules26020427. PMC 7830519. PMID 33467470.
  3. ^ Rocke, Zoe; Belyayeva, Mariya (2023), "Subacute Sclerosing Panencephalitis", StatPearls, Treasure Island (FL): StatPearls Publishing, PMID 32809508, retrieved 2024-01-19