Heavy chain may refer to:
- Immunoglobulin heavy chain, a subunit of antibodies
- Heavy-chain antibody, an antibody composed of heavy chains only
- Heavy chain disease, a disease affecting antibody heavy chain production
- Myosin heavy chain, a subunit of myosin II
- Myosin-heavy-chain kinase, an enzyme that catalyses the phosphorylation of myosin heavy chains
This disambiguation page lists articles associated with the title Heavy chain.
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