Harry Selker is an American physician and medical researcher at Tufts University School of Medicine, where he serves as Dean of the Clinical and Translational Science Institute and Executive Director of the Institute for Clinical Research and Health Policy Studies.[1][2][3] He is known for creating a class of "predictive instruments" built into electrocardiograph machines that help hospitals triage cardiac patients, and assist physician decision-making.[4][5][6]

Early life and education edit

Raised in Seattle, Washington,[4] Selker attended Reed College,[7] followed by medical school at Brown University. He later earned a Masters of Science in Public Health at the University of California Los Angeles, where he was a Robert Wood Johnson Foundation Clinical Scholar.[2]

Career edit

Starting in the 1990s, Selker devised a series of mathematical models for medical decision-making called "predictive instruments". These software tools can be loaded onto electrocardiograph machines or other medical devices. Using patient demographic information and analysis of the data from the medical device itself, the predictive instrument generates a probability in real-time of whether the patient was having a heart attack, or would likely need a particular treatment.[5] This software was subsequently included a number of common medical devices.[8][9]

Selker has led a number of studies relating to the glucose-insulin-potassium treatment cocktail known as GIK.[10] In 2012, his IMMEDIATE Trial showed that early administration of GIK made cardiac arrest or death after a heart attack less likely, and reduced the amount of damage to the heart itself by 80%.[4][11][12]

Selker is the author of two books: The Affordable Care Act as a National Experiment: Health Policy Innovations and Lessons, and Emergency Diagnostic Tests for Cardiac Ischemia.[13][14]

References edit

  1. ^ Riemer, Emily (7 May 2021). "Niclosamide, an old drug being put to new use in COVID-19 patients". ABC WCBV5 Boston. Retrieved 11 December 2023.
  2. ^ a b Pilar, Matthew (16 April 2021). "Biologics Clinical Research: The Year's Best". Bioprocess Online. Retrieved 11 December 2023.
  3. ^ "Harry P. Selker, MD, MSPH".
  4. ^ a b c Rath, Arun (23 September 2016). "This Doctor Is Trying To Stop Heart Attacks In Their Tracks". National Public Radio. Retrieved 11 December 2023.
  5. ^ a b Campbell, Paulette (Fall 2000). "Improving Emergency Room Diagnosis of Heart Attack Risk". NCRR Reporter. Retrieved 11 December 2023.
  6. ^ "AFMR Outstanding Investigator Award goes to Harry Selker". Research Activities. January 1998. Retrieved 11 December 2023.
  7. ^ "Faculty Profile: Harry P. Selker, MD, MSPH".
  8. ^ "ACI-TIPI Application Note" (PDF).
  9. ^ "New enhancements to the Philips HeartStart MRx support fast triage of STEMI patients". Cardiovascular News. 1 May 2009. Retrieved 11 December 2023.
  10. ^ "Study: Medics May Save Lives with Cardiac Cocktail". Journal of Emergency Medical Services. 30 March 2012. Retrieved 11 December 2023.
  11. ^ Selker, Harry P.; Beshansky, Joni R.; Sheehan, Patricia R.; Massaro, Joseph M.; Griffith, John L.; d'Agostino, Ralph B.; Ruthazer, Robin; Atkins, James M.; Sayah, Assaad J.; Levy, Michael K.; Richards, Michael E.; Aufderheide, Tom P.; Braude, Darren A.; Pirrallo, Ronald G.; Doyle, Delanor D.; Frascone, Ralph J.; Kosiak, Donald J.; Leaming, James M.; Van Gelder, Carin M.; Walter, Gert-Paul; Wayne, Marvin A.; Woolard, Robert H.; Opie, Lionel H.; Rackley, Charles E.; Apstein, Carl S.; Udelson, James E. (9 May 2012). "Out-of-Hospital Administration of Intravenous Glucose-Insulin-Potassium in Patients With Suspected Acute Coronary Syndromes". Journal of the American Medical Association. 307 (18): 1925–1933. doi:10.1001/jama.2012.426. PMC 4167391. PMID 22452807. Retrieved 11 December 2023.
  12. ^ Mandal, Ananya (28 Mar 2012). "Heart attack could be treated best with cheap mix of three injections". News-Medical.Net. Retrieved 11 December 2023.
  13. ^ Selker, Harry P., ed. (2021). The Affordable Care Act as a National Experiment. doi:10.1007/978-3-030-66726-9. ISBN 978-3-030-66725-2. S2CID 69165961.
  14. ^ "Book Review: Emergency Diagnostic Tests for Cardiac Ischemia". Annals of Internal Medicine. October 1998. Retrieved 11 December 2023.