Halimadienyl-diphosphate synthase (EC 5.5.1.16, Rv3377c, halimadienyl diphosphate synthase, tuberculosinol diphosphate synthase, halima-5(6),13-dien-15-yl-diphosphate lyase (cyclizing)) is an enzyme with systematic name halima-5,13-dien-15-yl-diphosphate lyase (decyclizing).[1] This enzyme catalyses the following chemical reaction
| Halimadienyl-diphosphate synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 5.5.1.16 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- geranylgeranyl diphosphate tuberculosinyl diphosphate
This enzyme requires Mg2+ for activity.
References edit
- ^ Nakano C, Okamura T, Sato T, Dairi T, Hoshino T (February 2005). "Mycobacterium tuberculosis H37Rv3377c encodes the diterpene cyclase for producing the halimane skeleton". Chemical Communications (8): 1016–8. doi:10.1039/b415346d. PMID 15719101.
External links edit
- Halimadienyl-diphosphate+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
