Glycine oxidase (EC 1.4.3.19) is an enzyme with systematic name glycine:oxygen oxidoreductase (deaminating).[1][2] This enzyme catalyses the following chemical reaction
| Glycine oxidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
 Glycine oxidase tetramer, Geobacillus kaustophilus | |||||||||
| Identifiers | |||||||||
| EC no. | 1.4.3.19 | ||||||||
| CAS no. | 39307-16-9 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- glycine + H2O + O2 glyoxylate + NH3 + H2O2 (overall reaction)
- (1a) glycine + O2 2-iminoacetate + H2O2
- (1b) 2-iminoacetate + H2O glyoxylate + NH3
This flavoenzyme containing non-covalently bound FAD.
References edit
- ^ Job V, Marcone GL, Pilone MS, Pollegioni L (March 2002). "Glycine oxidase from Bacillus subtilis. Characterization of a new flavoprotein". The Journal of Biological Chemistry. 277 (9): 6985–93. doi:10.1074/jbc.M111095200. PMID 11744710.
- ^ Nishiya Y, Imanaka T (November 1998). "Purification and characterization of a novel glycine oxidase from Bacillus subtilis". FEBS Letters. 438 (3): 263–6. doi:10.1016/s0014-5793(98)01313-1. PMID 9827558.
External links edit
- Glycine+oxidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
