Gap junction beta-5 protein (GJB5), also known as connexin-31.1 (Cx31.1), is a protein that in humans is encoded by the GJB5 gene.[5]

GJB5
Identifiers
AliasesGJB5, CX31.1, gap junction protein beta 5
External IDsOMIM: 604493; MGI: 95723; HomoloGene: 3858; GeneCards: GJB5; OMA:GJB5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_005268

NM_010291

RefSeq (protein)

NP_005259

NP_034421

Location (UCSC)Chr 1: 34.76 – 34.76 MbChr 4: 127.25 – 127.25 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Function

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Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family.[5]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000189280Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042357Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ a b "Entrez Gene: gap junction protein".

Further reading

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This article incorporates text from the United States National Library of Medicine, which is in the public domain.