Frank Horton may refer to:
- Frank Horton (New York politician) (1919–2004), United States Representative from New York
- Frank Horton (physicist) (1878–1957), British physicist
- Frank E. Horton (born 1939), American educator and administrator
- Frank L. Horton (1918–2004), American antiques dealer and museum director
- Frank O. Horton (1882–1948), United States Representative from Wyoming
- Frank Reed Horton (1896–1966), United States educator
This disambiguation page lists articles about people with the same name.
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