Denzil Holles may refer to:
- Denzil Holles (MP) (c. 1538–1590) MP for East Retford
- Denzil Holles, 1st Baron Holles (1599–1680), English statesman and writer
- Denzil Holles, 3rd Baron Holles (1675–c. 1692), English statesman
This disambiguation page lists articles about people with the same name.
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