DeLeon or De Leon may refer to:
- DeLeon (surname)
- Deleon Richards (b. 1976), US female gospel singer
- DeLeon (band)
- 17934 Deleon, a main-belt asteroid discovered in 1999
- DeLeon Springs, Florida, a census-designated place in the US state of Florida
- De Leon, Texas, a city in the US state of Texas
- DeLeón Tequila
This disambiguation page lists articles associated with the title DeLeon.
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