A carboxylate transporter is a membrane transport protein that transports carboxylate.
They are responsible for the reabsorption of filtered carboxylate in renal physiology, resulting in a 100%[1] reabsorption in the proximal tubule.
In proximal tubule edit
In the renal proximal tubule, there are several kinds of carboxylate transporters in the apical membrane and the basolateral membrane.
Apical edit
- Na-monocarboxylate cotransporter
- 3Na-dicarboxylate cotransporter
- 3Na-tricarboxylate cotransporter
Basolateral edit
- H-monocarboxylate cotransporter[1]
- organic anion-dicarboxylate exchanger
References edit
- ^ a b Walter F., PhD. Boron. Medical Physiology: A Cellular And Molecular Approaoch. Elsevier/Saunders. ISBN 1-4160-2328-3. Page 799