Ayeni may refer to:
- Adekunle Ayeni, Nigerian public relations practitioner, journalist, trained scientist and businessman
- Bosun Ayeni (born 1978), Nigerian footballer
- John Olatunde Ayeni (born 1967), Nigerian lawyer, investor and business magnate
- Kayode Ayeni (born 1987), American basketball player
- Phillip Ayeni (1949–2017), Navy Captain and first Administrator of Bayelsa State, Nigeria
- Tayo Ayeni (born 1962), Nigerian businessman
This disambiguation page lists articles about people with the same name.
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