Angelicin synthase (EC 1.14.13.115, CYP71AJ4 (gene)) is an enzyme with systematic name (+)-columbianetin,NADPH:oxygen oxidoreductase.[1] This enzyme catalyses the following chemical reaction:
| Angelicin synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC no. | 1.14.13.115 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
- (+)-columbianetin + NADPH + H+ + O2 angelicin + NADP+ + acetone + 2 H2O
Angelicin synthase is a P450 monooxygenase enzyme.
References edit
- ^ Larbat R, Hehn A, Hans J, Schneider S, Jugdé H, Schneider B, Matern U, Bourgaud F (February 2009). "Isolation and functional characterization of CYP71AJ4 encoding for the first P450 monooxygenase of angular furanocoumarin biosynthesis". The Journal of Biological Chemistry. 284 (8): 4776–85. doi:10.1074/jbc.M807351200. PMID 19098286.
External links edit
- Angelicin+synthase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
