Andrew Fraser Read FRS[1] is Evan Pugh professor of biology and entomology at Pennsylvania State University and the Director of the Huck Institutes of the Life Sciences.[2][3][4][5][6][7][8]
Andrew Read | |
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![]() Andrew Read in 2015, portrait via the Royal Society | |
Born | Andrew Fraser Read |
Nationality |
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Alma mater |
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Awards | |
Scientific career | |
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Institutions | |
Thesis | Comparative analyses of reproductive tactics (1989) |
Doctoral advisor | Paul H. Harvey |
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Education
editRead was educated at the University of Otago where he was awarded a Bachelor of Science degree in 1984.[9] He moved on to the University of Oxford where he was awarded a Doctor of Philosophy degree in 1989 for research supervised by Paul H. Harvey.[10]
Awards and honours
editRead was elected a Fellow of the Royal Society (FRS) in 2015. His certificate of election reads:
Andrew Read's work has revealed the evolutionary forces that shape pathogen virulence, infectivity, vaccine escape and drug resistance in a number of significant human infections. His work on malaria has provided a substantial body of experimental evidence to show that within-host selective pressures drive the evolution of both virulence and drug resistance. Integrating mathematical models with his experimental evidence, he proposed the controversial hypothesis that some vaccines can prompt evolution of more virulent pathogen strains. Recently he confirmed this hypothesis by evolving rodent malaria parasites in mice immunised with a candidate human malaria vaccine and showing virulence increased as predicted. He also developed both the theory and the proof of principle for the production of evolution-proof insecticides and provided the critical experimental evidence that animals have genetic variation in tolerance, a host defence mechanism which complements the more conventionally studied resistance.[1]
References
edit- ^ a b "Professor Andrew Read FRS". London: The Royal Society. Archived from the original on 2 May 2015.
- ^ Andrew F. Read publications indexed by Google Scholar
- ^ Andrew Read at TEDMED 2012: The bugs are getting smarter. Are we? on YouTube
- ^ West, S.A.; Lively, C.M.; Read, A.F. (1999). "A pluralist approach to sex and recombination". Journal of Evolutionary Biology. 12 (6): 1003–1012. doi:10.1046/j.1420-9101.1999.00119.x.
- ^ Gandon, S.; MacKinnon, M. J.; Nee, S.; Read, A. F. (2001). "Imperfect vaccines and the evolution of pathogen virulence". Nature. 414 (6865): 751–756. Bibcode:2001Natur.414..751G. doi:10.1038/414751a. hdl:1842/711. PMID 11742400. S2CID 4303357.
- ^ Read, A. F. (2001). "The Ecology of Genetically Diverse Infections". Science. 292 (5519): 1099–1102. Bibcode:2001Sci...292.1099R. doi:10.1126/science.1059410. PMID 11352063. S2CID 9371172.
- ^ Andrew F. Read's publications indexed by the Scopus bibliographic database. (subscription required)
- ^ Kouyos, R. D.; Metcalf, C. J.; Birger, R; Klein, E. Y.; Abel Zur Wiesch, P; Ankomah, P; Arinaminpathy, N; Bogich, T. L.; Bonhoeffer, S; Brower, C; Chi-Johnston, G; Cohen, T; Day, T; Greenhouse, B; Huijben, S; Metlay, J; Mideo, N; Pollitt, L. C.; Read, A. F.; Smith, D. L.; Standley, C; Wale, N; Grenfell, B (2014). "The path of least resistance: Aggressive or moderate treatment?". Proceedings of the Royal Society B: Biological Sciences. 281 (1794): 20140566. doi:10.1098/rspb.2014.0566. PMC 4211439. PMID 25253451.
- ^ "Andrew F. Read, Evan Pugh Professor of Biology and Entomology and Eberly Professor of Biotechnology". Pennsylvania State University. Archived from the original on 2 February 2014.
- ^ Read, Andrew Fraser (1989). Comparative analyses of reproductive tactics (DPhil thesis). University of Oxford. OCLC 46544592.