AIS may refer to:

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  • AIS, IATA code for Arorae Island Airport, Kiribati
  • Ais, Etruscan word meaning 'god'
  • Ais people, a Native American tribe living on the Atlantic coast of Florida, U.S.
  • Ais, an alternate spelling of Eyeish, a native American tribe in Texas, U.S.
  • American Indycar Series (1988–2005), a former American auto racing series