AGBL4

ATP/GTP binding protein like 4 is a protein that in humans is encoded by the AGBL4 gene.

AGBL4
Identifiers
Aliases	AGBL4, CCP6, ATP/GTP binding protein-like 4, ATP/GTP binding protein like 4, AGBL carboxypeptidase 4
External IDs	OMIM: 616476 MGI: 1918244 HomoloGene: 84880 GeneCards: AGBL4
Gene location (Human) Chr. Chromosome 1 (human) Band 1p33 Start 48,532,854 bp End 50,023,954 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4|4 C7- D1 Start 110,254,858 bp End 111,521,521 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in prefrontal cortex Brodmann area 23 Brodmann area 9 middle temporal gyrus right uterine tube islet of Langerhans pituitary gland hypothalamus anterior pituitary nucleus accumbens Top expressed in spermatid seminiferous tubule spermatocyte Jacobson's organ superior frontal gyrus substantia nigra supraoptic nucleus sensory ganglion hippocampus proper cerebellar cortex More reference expression data BioGPS n/a
Gene ontology Molecular function carboxypeptidase activity tubulin binding zinc ion binding peptidase activity hydrolase activity metallopeptidase activity metal ion binding metallocarboxypeptidase activity Cellular component cytoplasm ciliary basal body centriole cytosol Golgi apparatus cell projection cytoskeleton Biological process C-terminal protein deglutamylation protein side chain deglutamylation proteolysis protein deglutamylation defense response to virus Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 84871 78933 Ensembl ENSG00000186094 ENSMUSG00000061298 UniProt Q5VU57 Q09LZ8 RefSeq (mRNA) NM_032785 NM_001323573 NM_001323574 NM_001323575 NM_001048189 NM_001284190 NM_030231 RefSeq (protein) NP_001310502 NP_001310503 NP_001310504 NP_116174 NP_001041654 NP_001271119 NP_084507 Location (UCSC) Chr 1: 48.53 – 50.02 Mb Chr 4: 110.25 – 111.52 Mb PubMed search
Wikidata
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Further reading

• Trynka G, Zhernakova A, Romanos J, Franke L, Hunt KA, Turner G, Bruinenberg M, Heap GA, Platteel M, Ryan AW, de Kovel C, Holmes GK, Howdle PD, Walters JR, Sanders DS, Mulder CJ, Mearin ML, Verbeek WH, Trimble V, Stevens FM, Kelleher D, Barisani D, Bardella MT, McManus R, van Heel DA, Wijmenga C (August 2009). "Coeliac disease-associated risk variants in TNFAIP3 and REL implicate altered NF-kappaB signalling". Gut. 58 (8): 1078–83. doi:10.1136/gut.2008.169052. PMID 19240061. S2CID 17111427.
• Rose JE, Behm FM, Drgon T, Johnson C, Uhl GR (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Molecular Medicine. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
• Wu HY, Rong Y, Correia K, Min J, Morgan JI (January 2015). "Comparison of the enzymatic and functional properties of three cytosolic carboxypeptidase family members". The Journal of Biological Chemistry. 290 (2): 1222–32. doi:10.1074/jbc.M114.604850. PMC 4294487. PMID 25416787.
• Lin PC, Lin JK, Lin CH, Lin HH, Yang SH, Jiang JK, Chen WS, Chou CC, Tsai SF, Chang SC (December 2015). "Clinical Relevance of Plasma DNA Methylation in Colorectal Cancer Patients Identified by Using a Genome-Wide High-Resolution Array". Annals of Surgical Oncology. 22 (Suppl 3): S1419-27. doi:10.1245/s10434-014-4277-2. PMID 25472652. S2CID 13377596.