The 2016 Karshi Challenger was a professional tennis tournament played on hard courts. It was the tenth edition of the tournament which was part of the 2016 ATP Challenger Tour. It took place in Qarshi, Uzbekistan between 2 and 7 May 2016.
| 2016 Karshi Challenger | |
|---|---|
| Date | 2–7 May |
| Edition | 10th |
| Draw | 32S / 16D |
| Prize money | $50,000+H |
| Surface | Hard |
| Location | Qarshi, Uzbekistan |
| Champions | |
| Singles | |
 Marko Tepavac | |
| Doubles | |
 Enrique López Pérez /  Jeevan Nedunchezhiyan | |
Singles main-draw entrants edit
Seeds edit
| Country | Player | Rank1 | Seed |
|---|---|---|---|
 ISR
|
Dudi Sela | 78 | 1 |
 RUS
|
Karen Khachanov | 128 | 2 |
 MDA
|
Radu Albot | 151 | 3 |
 KAZ
|
Aleksandr Nedovyesov | 197 | 4 |
| ISR
|
Amir Weintraub | 198 | 5 |
 UKR
|
Denys Molchanov | 224 | 6 |
| KAZ
|
Dmitry Popko | 230 | 7 |
| RUS
|
Aslan Karatsev | 216 | 8 |
- 1 Rankings as of April 25, 2016.
Other entrants edit
The following players received wildcards into the singles main draw:
Pavel Tsoy- Sanjar Fayziev
- Temur Ismailov
- Shonigmatjon Shofayziyev
The following players received entry from the qualifying draw:
Sergey Betov
Denis Matsukevich
Francesco Vilardo- Richard Muzaev
The following player received entry as a lucky loser:
Champions edit
Singles edit
Marko Tepavac def. 
Dudi Sela, 2–6, 6–3, 7–6(7–4)
Doubles edit
Enrique López Pérez / 
Jeevan Nedunchezhiyan def. 
Aleksandre Metreveli / 
Dmitry Popko, 6–1, 6–4
