The men's 4 x 50 metre medley relay at the 2013 IPC Swimming World Championships was held at the Parc Jean Drapeau Aquatic Complex in Montreal from 12 to 18 August.
Medalists edit
| Points | Gold | Silver | Bronze |
| 20 points | Dmytro Vynohradets S3 Oleksandr Komarov SB6 Yevheniy Bohodayko S7 Eskender Mustafaiev S4  Ukraine
|
Miguel Angel Martinez Tajuelo S3 Ricardo Ten SB4 Jaime Bailon Galindo S8 Sebastian Rodriguez S5  Spain
|
Dmitrii Kokarev S2 Alexey Fomenkov SB6 Denis Tarasov S8 Aleksei Lyzhikhin S4  Russia
|