Nathalie Dechy and Mara Santangelo won the tournament in 2009, but Dechy retired from tennis later in the year and Santangelo chose to not participate this year.
Iveta Benešová and Barbora Záhlavová-Strýcová won in the final 3–6, 6–4, [10–8] against Anna-Lena Grönefeld and Vania King.
| Doubles | |
|---|---|
| 2010 Monterrey Open | |
| Champion |  Iveta Benešová Barbora Záhlavová-Strýcová |
| Runner-up |  Anna-Lena Grönefeld Vania King |
| Score | 3–6, 6–4, [10–8] |
Seeds edit
Anna-Lena Grönefeld / 
Vania King (final)
Iveta Benešová / Barbora Záhlavová-Strýcová (champions)- Andrea Hlaváčková / Lucie Hradecká (first round)
- Vladimíra Uhlířová / Renata Voráčová (first round)
Draw edit
Key edit
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- SE = Special exempt
- PR = Protected ranking
- ITF = ITF entry
- JE = Junior exempt
- w/o = Walkover
- r = Retired
- d = Defaulted
- SR = Special ranking
Draw edit
| First round | Quarterfinals | Semifinals | Finals | ||||||||||||||||||||||||
| 1 | A-L Grönefeld V King
| 6 | 6 | ||||||||||||||||||||||||
C Gullickson M Krajicek
| 1 | 2 | 1 | A-L Grönefeld V King
| 4 | 6 | [10] | ||||||||||||||||||||
 M Kondratieva S Lefèvre
| 1 | 3 | A Pavlyuchenkova K Zakopalová
| 6 | 3 | [5] | |||||||||||||||||||||
| A Pavlyuchenkova K Zakopalová
| 6 | 6 | 1 | A-L Grönefeld V King
| 6 | 6 | [10] | ||||||||||||||||||||
| 4 | V Uhlířová R Voráčová
| 4 | 2 |  S Errani R Vinci
| 7 | 3 | [6] | ||||||||||||||||||||
| S Errani R Vinci
| 6 | 6 | S Errani R Vinci
| 63 | 6 | [10] | |||||||||||||||||||||
| J Craybas J Görges
| 6 | 6 | J Craybas J Görges
| 7 | 3 | [4] | |||||||||||||||||||||
| WC |  MF Alves D Múñoz Gallegos
| 1 | 1 | 1 | A-L Grönefeld V King
| 6 | 4 | [8] | |||||||||||||||||||
| WC | A Védy M Washington
| 4 | 4 | 2 | I Benešová B Záhlavová-Strýcová
| 3 | 6 | [10] | |||||||||||||||||||
J Coin M-È Pelletier
| 6 | 6 | J Coin M-È Pelletier
| 7 | 7 | ||||||||||||||||||||||
 L Domínguez Lino A Parra Santonja
| 5 | 6 | [10] | L Domínguez Lino A Parra Santonja
| 60 | 5 | |||||||||||||||||||||
| 3 | A Hlaváčková L Hradecká
| 7 | 2 | [5] | J Coin M-È Pelletier
| 5 | 5 | ||||||||||||||||||||
| ALT | N Bratchikova K Wörle
| 3 | 7 | [10] | 2 | I Benešová B Záhlavová-Strýcová
| 7 | 7 | |||||||||||||||||||
| A Medina Garrigues M Shaughnessy
| 6 | 65 | [12] | A Medina Garrigues M Shaughnessy
| 2 | 63 | |||||||||||||||||||||
 O Savchuk R Zalameda
| 4 | 65 | 2 | I Benešová B Záhlavová-Strýcová
| 6 | 7 | |||||||||||||||||||||
| 2 | I Benešová B Záhlavová-Strýcová
| 6 | 7 | ||||||||||||||||||||||||