The women's 4 × 100 metres relay event at the 2004 African Championships in Athletics was held in Brazzaville, Republic of the Congo on July 16.
Results edit
| Rank | Nation | Competitors | Time | Notes |
|---|---|---|---|---|
 |
 Nigeria |
Gloria Kemasuode, Mercy Nku, Damola Osayomi, Endurance Ojokolo | 44.32 | |
 |
 South Africa |
Dikeledi Moropane, Heide Seyerling, Adri Schoeman, Geraldine Pillay | 44.42 | |
 |
 Senegal |
Fatoumata Coly, Aïda Diop, Aissatou Badji, Aminata Diouf | 45.21 | |
| 4 |  Cameroon |
Jacquette Mekoa Mve, Charlotte Mebenga, Blandine Fonkeu, Delphine Atangana | 45.63 | |
| 5 |  Ghana |
Mercy Tabiri, Smart Abbey, Aisha Pinamang, Gifty Addy | 46.07 | |
| 6 |  Burkina Faso |
Mariette Mien, Aïssata Soulama, Sarah Tondé, Béatrice Kamboulé | 46.77 | NR |
 Republic of the Congo |
Juscarelle Kibouanga, Michelle Banga Moundzoula, Solène Eboulabeka, Melanie Atsio-Gouamali | DQ |