Gamma-1-syntrophin is a protein that in humans is encoded by the SNTG1 gene.[5][6]

SNTG1
Identifiers
AliasesSNTG1, G1SYN, SYN4, syntrophin gamma 1
External IDsOMIM: 608714; MGI: 1918346; HomoloGene: 56834; GeneCards: SNTG1; OMA:SNTG1 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001290390
NM_001290392
NM_001290393
NM_027671

RefSeq (protein)

NP_001277319
NP_001277321
NP_001277322
NP_081947

Location (UCSC)Chr 8: 49.91 – 50.8 MbChr 1: 8.36 – 9.3 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

The protein encoded by this gene is a member of the syntrophin family. Syntrophins are cytoplasmic peripheral membrane proteins that typically contain 2 pleckstrin homology (PH) domains, a PDZ domain that bisects the first PH domain, and a C-terminal domain that mediates dystrophin binding. This gene is specifically expressed in the brain. Transcript variants for this gene have been described, but their full-length nature has not been determined.[6]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000147481Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000025909Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Piluso G, Mirabella M, Ricci E, Belsito A, Abbondanza C, Servidei S, Puca AA, Tonali P, Puca GA, Nigro V (Jun 2000). "Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells". J Biol Chem. 275 (21): 15851–60. doi:10.1074/jbc.M000439200. PMID 10747910.
  6. ^ a b "Entrez Gene: SNTG1 syntrophin, gamma 1".

Further reading

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