Eukaryotic translation initiation factor 5 is a protein that in humans is encoded by the EIF5 gene.[5][6]

EIF5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesEIF5, EIF-5, EIF-5A, eukaryotic translation initiation factor 5, Eukaryotic initiation factor 5
External IDsOMIM: 601710; MGI: 95309; HomoloGene: 49610; GeneCards: EIF5; OMA:EIF5 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_183004
NM_001969

NM_173363
NM_178041

RefSeq (protein)

NP_001960
NP_892116

NP_775539
NP_829887

Location (UCSC)Chr 14: 103.33 – 103.35 MbChr 12: 111.5 – 111.51 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

EIF5 is a GTPase-activating protein.[7]


References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100664Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021282Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Si K, Das K, Maitra U (Aug 1996). "Characterization of multiple mRNAs that encode mammalian translation initiation factor 5 (eIF-5)". J Biol Chem. 271 (28): 16934–8. doi:10.1074/jbc.271.28.16934. PMID 8663286.
  6. ^ "Entrez Gene: EIF5 eukaryotic translation initiation factor 5".
  7. ^ Das S, Ghosh R, Maitra U (March 2001). "Eukaryotic translation initiation factor 5 functions as a GTPase-activating protein". J. Biol. Chem. 276 (9): 6720–6. doi:10.1074/jbc.M008863200. PMID 11092890.
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  • Cap-dependent translation initiation from Nature Reviews Microbiology. A good image and overview of the function of initiation factors
  • PDBe-KB provides an overview of all the structure information available in the PDB for Human Eukaryotic translation initiation factor 5 (EIF5)

Further reading

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