Mitochondrial import inner membrane translocase subunit Tim9 is an enzyme that in humans is encoded by the TIMM9 gene.[5][6][7]

TIMM9
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTIMM9, TIM9, TIM9A, translocase of inner mitochondrial membrane 9
External IDsOMIM: 607384; MGI: 1353436; HomoloGene: 40847; GeneCards: TIMM9; OMA:TIMM9 - orthologs
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001024853
NM_001024854
NM_001286203
NM_013896

RefSeq (protein)

NP_001020024
NP_001020025
NP_001273132
NP_038924

Location (UCSC)Chr 14: 58.41 – 58.43 MbChr 12: 71.17 – 71.18 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

TIMM9 belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space.

These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.[supplied by OMIM][7]

References

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  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000100575Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000021079Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Jin H, Kendall E, Freeman TC, Roberts RG, Vetrie DL (Feb 2000). "The human family of Deafness/Dystonia peptide (DDP) related mitochondrial import proteins". Genomics. 61 (3): 259–67. doi:10.1006/geno.1999.5966. PMID 10552927.
  6. ^ Muhlenbein N, Hofmann S, Rothbauer U, Bauer MF (Mar 2004). "Organization and function of the small Tim complexes acting along the import pathway of metabolite carriers into mammalian mitochondria". J Biol Chem. 279 (14): 13540–6. doi:10.1074/jbc.M312485200. PMID 14726512.
  7. ^ a b "Entrez Gene: TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast)".

Further reading

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